Tag Archives: chemo

Cancer Update 18: New Chemo and Radiation

This is a cancer update.  In response to a recent PET scan, I started my second set of chemo rounds on July 10th.  This time, I plan to have 6 rounds instead of just 4.  While my new rib tumor is much smaller than the first time, we want to give it more rounds this time, so we make sure we get everything. 

NGS:
We reanalyzed my tumor using Next Generation Sequencing.  This amazing new technology allow scientists to sequencing many different pieces of DNA in the same sample.  In this case, instead of a biopsy, they took a blood sample and looked for their targets, a particular set of gene, in the sample.  Even though my tumor cells would be a tiny minority of the total cells in my blood, NGS can still find them and sequence them individually.  Happily, analysis shows that my new tumor is genetically the same as my old one, so it should respond to chemotherapy in the same way, just as we hoped.

I also took a monitoring test that finds and counts the number of tumor cells in my blood, which will help us track progress in the future.  This is a different technology called real-time PCR.  I have worked extensively with both of these technologies at my job at Quest Diagnostics, and in my current consulting business.

Chemotherapy:
The July 10th chemo itself went well.  Usually, the week after is the worst part.  I take some medications in the few days surrounding the actual infusion.  They counter act many of the side effects I might normally feel like nausea and fatigue. I stop taking some of these medications on Monday, so Tuesday and Wednesday of the following week are usually the worst.  This time, since I’m so much healthier in general than last time, my “bad week” was much better, just a little sleepiness and a little skin irritation, both very manageable. I actually started my second new round yesterday with another infusion.

Kathy and I enjoy a celebratory bag of Doritos during yesterday’s infusion. Don’t mind my pasty complexion. I pretty much always look like that. Photo credit: Kathy Johnson

Radiation:
As it turns out, my radiation oncologist says they can treat the rib tumor again, since I didn’t get too much radiation the first time.  I’ve already had my mapping session, and I start radiation next week.  This will greatly accelerate rib tumor healing.  It will likely make me even sleepier next week.  So if you call or text next week, you may not hear from me for a while! But weeks 2 and 3 will be better, because of my better overall health.  Outdoor meetings are definitely possible!

Thank you so much for your continued prayers!  It’s definitely helping!

Don’t fear, but be smart,
Erik

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Cancer Update 9: “Wednesday”

Friends,

Today, I just have a brief update.

My 3rd round of chemo started with an infusion yesterday. For the first few days of a new round, I’m on some extra medication that counteracts some of the negative side-effects of the chemo agents.  So while I’m on those medications, I’m actually feeling really good!  Those medications will run out on Sunday, so starting Monday is when I start “Fatigue Week”, which for me has been just sleepiness.  Until then, I’m actually feeling good and can do my normal 2 short walks a day, and even do my stair exercises.  “Fatigue Week” has generally lasted just from Monday to Thursday or so, and then I’ve been turning a corner on Friday, which I expect to happen this week as well. 

I usually go on 2 short walks a day. Then I do 5 sets of stairs after my walk, trying to regain muscle mass after my long hospital stay. It’s already making a difference!

I caught a very mild viral infection this time, and had to be more strict on having visitors.  Fewer visitors, and always meeting out on the patio from now on.  Despite that, my White Blood Cell count remained fine for a person on chemo, so my 3rd round started on time.  I also finished my radiation treatments on Friday, November 8th, so I’m very happy to be done with that.  Now it’s just chemo, and immunotherapy starting with my next chemo round in early December.  People tolerate immunotherapy very well.

Because I’m halfway through chemo, Kathy remarked that it felt like “Wednesday”, like we just have to endure a few more days before the welcome end.  Everyone from students to adults in the workplace know what that feels like!

Right now, I’m thinking as if my chemo journey will end around December 14th, when I’ll emerge from my “bad week” for that round.  Then I’ll need to start working out, regaining the strength I lost while in the hospital.  It’ll take me a few months to get back to my ideal weight, and be ready to travel again.  So by Christmastime, I should be mostly back to normal.

Results continue to be very good, and my prognosis remains very good!

Thanks again for all your prayers!  We continue to pray that my tumor tissue will become lung tissue, and not just scar tissue, to maximize my hiking, backpacking and skiing abilities, some of my favorite activities!

Also pray that my broken rib will heal quickly! We still have no idea how long it will take, but it will be much longer than the usual 6 weeks, since the pieces are not sitting right next to each other yet, but have to grow together before they can mend.

Don’t fear, but be smart,
Erik

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